l The most important indicator for early negative exclusion of AMI.
Myoglobin, one of the earliest detectable markers after the onset of acute myocardial infarction (AMI), begins to be released into the blood within 1 hour after the onset of AMI. As its diagnostic specificity is not high, mainly negative results can be used for early exclusion diagnosis.
l More sensitive indicator for AMI recurrence monitoring and reperfusion therapy monitoring.
Myoglobin returns to baseline concentration within the first day after the attack and then rises rapidly when there is another infarction, forming a multi-peak phenomenon that can counteract the periodic spontaneous coronary reinfarction and reperfusion of locally ischemic myocardium
l Combined test for the four indicators of heart attack
The time of elevation of cTnI, CK-MB, Myo, and H-FABP in blood, time of reaching peak in blood, time to normalization, and clinical significance are different. The detection of AMI is not sufficient if a single indicator is tested. Therefore, simultaneous rapid detection of these three markers can improve early sensitivity and late specificity in the diagnosis of heart disease.