Currently the only indicator for predicting sepsis
Recent European multicenter study results show that HBP is an early diagnostic marker of infection-related organ dysfunction and can reliably predict whether infected patients will progress to severe sepsis within 72 hours (median,10.5h).
Predict the trend of blood pressure, guide of fluid resuscitation and the use of booster drugs
HBP concentration is negatively correlated with blood pressure. Continuous monitoring of HBP concentration can prompt infusion and booster therapy.
Sepsis diagnosis and risk stratification
High HBP level represents a higher critical value in septic shock while low concentration of HBP can be used as indicators of exclusion to rule out the risk of developing sepsis.
Both infection marker and pathogenic factor
HBP may be a potential target for drugs such as heparin, simvastatin, tezentan, etc. which can efectively reduce HBP levels in sepsis patients.
Meningitis: Cerebrospinal fluid HBP can discriminate viral and bacterial meningitis.
ALI/ARDS: HBP is a powerful indicator to aid diagnosis and predict ALI/ARDS.